Joint Patent for Research Collaboration between BIOTEC/NSTDA and SHISEIDO



Joint Patent for Research Collaboration between BIOTEC/NSTDA and SHISEIDO

BANGKOK, Thailand, 07 July 2008 -- The National Science and Technology Development Agency (NSTDA) of Thailand and Shiseido Co., Ltd. a leading cosmetic manufacturer in Japan announced they have filed a collaborative research technology patent in both Thailand and Japan. The filing of the joint research patent itself signifies a milestone achievement between researchers of both countries.

The research, conducted jointly by the National Center for Genetic Engineering and Biotechnology (BIOTEC) and Shiseido, identified potential activities in in-vitro tests in six plant species as following:
• Cinnamomum ilicioides possessing whitening effect, anti-aging effect, anti-skin roughness activity
• Lepisanthes fruticosa: anti-aging and slimming effects
• Fagraea fragrans: anti-aging and anti-skin roughness effects
• Pterocarpus indicus: anti-aging effect
• Boesenbergia regalis: whitening and anti-aging effects
• Aquilaria crassna: whitening and anti-aging effects

The findings will act as a catalyst for further research development of cosmetic ingredients and skin care products by Thai and Japanese researchers who are listed as inventors in the patent application.

“The joint research collaboration, started in December 2004, was conducted in full compliance with the CBD (Convention on Biological Diversity) and Thailand’s Plant Varieties Protection Act B.E. 2542,” said Dr. Kanyawim Kirtikara, the Executive Director of BIOTEC. “Information including the plant list and research plan was submitted to the Department of Agriculture and permissions were granted. We have expressed our intention to the Department of Agriculture to enter into a benefit-sharing agreement with the Royal Thai Government as soon as the Ministerial Regulation stipulating the protocol comes into effect. Currently, the Ministerial Regulation outlining the protocol for the benefit-sharing is in the process of drafting”.

A patent is designed to provide legal protection over an innovation against business competitors. However, BIOTEC/NSTDA and Shiseido assured that this patent will not affect Thai local communities which traditionally may have already used these six plants for various purposes. BIOTEC and Shiseido have made an agreement that Thai local communities can continue using the plant extracts. “This is an unprecedented move in Thailand for a patent to give favor to local community, and we hope it will set example for future practices, not only to protect our biodiversity, but also to give recognition to our indigenous knowledge,” said Dr. Kanyawim.

“It has been three and a half years since BIOTEC and Shiseido began the collaborative research and we are delighted to announce our research outcome to the public. This result demonstrates not only our collaborative achievement but also the distribution of scientific technology from Japan to Thailand which helps maintain good relationships and contributes to the long-term development of the two countries. Through the Shiseido Southeast Asia Research Center located at the Thailand Science Park, we look forward to making a contribution to Thailand’s culture of cosmetics and development of products for many years to come,” said Mr. Tsunehiko Iwai, Corporate Officer, Responsible for Technical Planning and Technical Affairs at Shiseido.

“It has long been NSTDA’s interest to collaborate with foreign partners in research and development. Our collaboration is based on the partnership concept, in which both partners co-invest and share results and benefits. NSTDA also gives importance to enhancing national research capabilities” said Prof. Dr. Chachanat Thebtaranonth, NSTDA Vice President and Executive Director of NSTDA Technology Management Center.


The National Center for Genetic Engineering and Biotechnology (BIOTEC), founded in 1983, is one of four technology centers under the auspices of the National Science and Technology Development Agency (NSTDA), an autonomous government agency. The Center is a leading research institute in Thailand and the region, with over 30 laboratories and 150 principle scientists conducting basic and applied research covering a wide spectrum from agricultural science to biomedical science and environmental science. BIOTEC has three research units located at Thailand Science Park and about ten specialized laboratories situated in universities and government agencies across the country. More information about BIOTEC is available at
About Shiseido 
Shiseido, established in 1872 as a western-style pharmacy, is number one in Japan’s cosmetic industry and the 6th worldwide. In the fiscal year 2007, the total amount of Shiseido’s R&D expenditure reached ¥ 17.4 billion, or 2.4 percent of ¥ 723 billion net sales. Shiseido’s R&D activities form a global network spanning five regions including Japan and approximately 1,000 researchers (including staff) are engaged in numerous research fields. Shiseido Southeast Asia Research Center, established in 2006, carries out comprehensive studies, not only to conduct research on the unique properties of plants but also to learn about the characteristics of local customers, including skin types, areas of concern, usage preferences tailored in accordance with local climate conditions like temperature and humidity. More information about Shiseido is available at



NSTDA, BIOTEC and Shiseido officers at the Press Briefing held in Thailand on 7 July 2008.


Posted on 7 July 2008.