On 18 August 2010, the Department of Mental Health, Ministry of Public Health handed over the SNP database, resulting from the study on genotype and pharmacogenomics of major depressive disorder in Thai population, to BIOTEC Genome Institute. The database contains 500,000 SNPs from 186 control datasets from the case-control major depressive disorder study conducted by the Rajanukul Institute of Mental Health. This database will be incorporated into BIOTEC ThaiSNP database, maintained by Genome Institute, making ThaiSNP the most comprehensive SNP database of Thai population.
Initiated in 2003, a collaboration project between BIOTEC, Mahidol University, Institut Pasteur, and the Centre National de Génotypage (CNG) France, collected intragenic SNP markers from 194 candidate genes of 32 healthy Thai volunteers’ DNA samples randomly chosen from 64 volunteers. The information derived from this project constituted the beginning of ThaiSNP database. In order to facilitate medical genetic scientists, the BIOTEC ThaiSNP database has collected SNPs from various SNP studies as well as from largescale SNP genotyping projects. The database allows search for Thai-specific SNPs as well as other ethnic SNPs reported in the public domain dbSNP from the National Center for Biotechnology Information (NCBI). Moreover, SNP locations from different populations can be displayed in a comparative view illustrating the underlying differences.
Dr. Chatree Banchuen (fifth from left ), Director-General of Department of Mental Health, Dr. Somvong Tragoonrung (fourth from left), Director of Genome Institute and Dr. Sissades Tongsima (third from left), Head of Biostatistics and Informatics Laboratory, BIOTEC at the hand-over ceremony
Posted on 24 August 2010.