SpirPro: Spirulina-Proteome Repository

Cyanobacteria have been experimentally used as a model for plants and bacteria, therefore many cyanobacteria, such asSynechocystis sp.Synechococcus sp., and Spirulina (Arthrospira) platensis, have been studied at the genomic and proteomic levels.


In the quest to understand the affect of fluctuating environmental temperatures on Spirulina mass cultivation, researchers performed proteomic analyses ofSpirulina under optimal and temperature stress conditions. The study led to the development of SpirPro, an integrated database for Spirulina. This database provides possible mechanisms, in term of protein-protein interaction networks and proteome-wide expression levels, underlying the temperature stress response of this cyanobacterium for use as model mechanisms for other photosynthetic organisms, such as plants, algae and other cyanobacteria. Moreover, proteome-wide domain identification is available in the database, which might be useful for further studies on protein-protein interaction domain analyses. SpirPro is publicly available on-line at http://spirpro.sbi.kmutt.ac.th.

This is a joint study between Biochemical Engineering and Pilot Plant Research and Development Laboratory and King Mongkut’s University of Technology Thonburi.

The full article can be accessed here.

Ref: Senachak, J., Cheevadhanarak, S. and Hongsthong, A. (2015). SpirPro: A Spirulina proteome database and web-based tools for the analysis of protein-protein interactions at the metabolic level in Spirulina (Arthrospira) platensis C1. BMC Bioinformatics, 16:233.


Posted on 28 September 2015