• Malaria
  
• Dengue Haemorragic Fever
  
• Tuberculosis
  
• HIV OIs
  
• Others
  

• understanding and applying knowledge of drug action and resistance with the emphasis on obtaining information which will be useful in clinical situations in Thailand ;
  
• identification, validation and expression of targets for drugs, diagnostics and vaccines, which could well develop as a niche area for Thailand ;
  
• generation of new compounds both from combinatorial biosynthesis or from natural products known through traditional knowledge of herbal remedies for malaria; and
  
• production, formulation and pre-clinical studies of a few drug candidates suited to the needs of Thailand and neighbouring countries.

Dengue Haemorragic Fever
Recommendations for research relative to dengue are:

• new technology in dengue diagnosis;
  
• basic pathogenic mechanisms of shock, leakage, and haemorrhagic diathesis, emphasising studies of autopsy or necropsy tissues or clinical specimen;
  
• viral physiology in Aedes aegypti, vector control;
  
• molecular epidemiology of dengue virus in Thailand: evolution of the viruses in different regions of the country, genotypes associated with virulence;
  
• vaccine
  
• clinical and physiology research; and
  
• basic research: molecular and cellular pathophysiology of dengue virus infection.

• development of new antituberculous drugs through screening of natural products
  
• improvement in screening methods
  
• characterisation of M. tuberculosis strains in Thailand and elucidation of the phenotype characteristics of various genotypes
  
• development of new diagnostic tests and new treatment protocols
  
• application of new methods in the study of the epidemiology of tuberculosis
  

• development of practical diagnostic kits which could be affordable in developing countries where the majority of patients live
  
• development of vaccines for the infections involved in AIDS/HIV, at the moment far from reality, at a cost which would make them accessible where needed.
  

• development of diagnostic kits for the detection of hepatitis B surface antigen (HBS Ag) in patients' sera;
  
• research on the problems of hepatitis B vaccine failure including detection and analysis of vaccine-escape mutants of hepatitis B viruses; and
  
• development of diagnostic kits that can be used to detect antigenically variant hepatitis C viruses, necessary due to high mutation rate of the hepatitis C viruses.