1. Investigating the medicinal potentials of microorganisms native to Thailand’s natural habitats
2. Establishing in vitro bioassays screening for agricultural and animal pest controls
3. Chemical profile library of non-ribosomal peptides
4. The eicosanoid biosynthesis pathway and its biological significance

1. Cytotoxicity tests against mammalian cell lines
2. Cytotoxicity tests against insect cell lines
3. Anti-human and animal infectious pathogens
4. Anti-plant disease pathogens
5. Mycoplasma testing of cultured cells

2010

Bunyapaiboonsri, T.; Yoiprommarat, S.; Srikitikulchai, P.; Srichomthong, K.; Lumyong, S. Oblongolides from the endophytic fungus Phomopsis sp. BCC 9789. J Nat Prod 2010, 73, 55-9.

Haritakun, R.; Sappan, M.; Suvannakad, R.; Tasanathai, K.; Isaka, M. An antimycobacterial cyclodepsipeptide from the entomopathogenic fungus Ophiocordyceps communis BCC 16475. J Nat Prod 2010, 73, 75-8.

2009

Chutrakul C, Boonruangprapa T, Suvannakad R, Isaka M, Sirithunya P, Toojinda T, Kirtikara K (2009) Ascherxanthone B from Aschersonia luteola, a new antifungal compound active against rice blast pathogen Magnaporthe grisea. J Appl Microbiol 107:1624-1631.

Isaka M, Palasarn S, Auncharoen P, Komwijit S, Jones EBG (2009) Acremoxanthones A and B, novel antibiotic polyketides from the fungus Acremonium sp. BCC 31806. Tetrahed Lett 50:284-287.

Pittayakhajonwut P, Sri-indrasutdhi V, Dramae A, Lapanun S, Suvannakad R, Tantichareon M (2009) Graphisins A and B from the Lichen Graphis tetralocularis. Aust J Chem 62: 389–391.

2008

Sandee D, Sivannuntakorn S, Vichai V, Kramyu J, Kirtikara K (2008) Up-regulation of microsomal prostaglandin E synthase-1 in COX-1 and COX-2 knock-out mouse fibroblast cell lines. Prostaglandins Other Lipid Mediat 88: 111-116.

Berkaew P, Soonthornchareonnon N, Salasawadee K, Chanthaket, R, Isaka M (2008) Aurocitrin and related polyketide metabolites from the wood-decay fungus Hypocrea sp. BCC 14122. J Nat Prod 71: 902–904.

Bunyapaiboonsri T, Veeranondha S, Boonruangprapa T, Somrithipol S (2008) Ramiferin, a bisphenol-sesquiterpene from the fungus Kionochaeta ramifera BCC 7585. Phytochemistry Letters 1:204–206.

Pittayakhajonwut P, Sohsomboon P, Dramae A, Suvannakad R, Lapanun S, Tantichareon M (2008) Antimycobacterial substances from Phaeosphaeria sp BCC8292. Planta medica 74 (3):281-286.

Isaka M, Chinthanom P, Veeranondha S, Supothina S, Luangsa-ard J (2008) Novel cyclopropyl diketones and 14-membered macrolides from the soil fungus Hamigera avellanea BCC 17816. Tetrahedron 64:11028–11033.

2007

Gale GA, Kirtikara K, Pittayakhajonwut P, Sivichai S, Thebtaranonth Y, Thongpanchang C, Vichai V (2007) In search of cyclooxygenase inhibitors, anti-Mycobacterium tuberculosis and anti-malarial drugs from Thai flora and microbes. Pharmacol Ther 115: 307-351.

Bunyapaiboonsri T, Yoiprommarat S, Intereya K, Kocharin K (2007) New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861. Chem Pharm Bull 55(2):304—307.

Isaka M, Boonkhao B, Rachtawee P, Auncharoen P (2007) A xanthocillin-like alkaloid from the insect pathogenic fungus Cordyceps brunnearubra BCC1395. J Nat Prod 70(4):656-658.

2006

Vichai V, Kirtikara K (2006) Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc. 1(3): 1112-1116.

Thongtan J, Saenboonrueng J, Rachtawee P, Isaka M (2006) An antimalarial tetrapeptide from the entomopathogenic fungus Hirsutella sp. BCC 1528. J Nat Prod 69 (4):713–714.

Namdaung U, Aroonrerk N, Suksamrarn S, Danwisetkanjana K, Saenboonrueng J, Arjchomphu W, Suksamrarn A (2006) Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus. Chem Pharm Bull (Tokyo) 54(10):1433-1436.

Chinworrungsee M, Kittakoop P, Saenboonrueng J, Kongsaeree P, Thebtaranonth Y (2006) Bioactive compounds from the seed fungus Menisporopsis theobromae BCC 3975. J Nat Prod 69(10):1404-1410.

Rukachaisirikul V, Chantaruk S, Tansakul C, Saithong S, Chaicharernwimonkoon L, Pakawatchai C, Isaka M, Intereya K (2006) A Cyclopeptide from the Insect Pathogenic Fungus Cordyceps sp. BCC 1788. J Nat Prod 69(2):305-307.

2005

Vichai V, Suyarnsesthakorn C, Pittayakhajonwut D, Sriklung K, Kirtikara K (2005) Positive feedback regulation of COX-2 expression by prostaglandin metabolites. Inflamm Res 54:163-72.

Rukachaisirikul V, Tansakul C, Saithong S, Pakawatchai C, Isaka M, Suvannakad R (2005) Hirsutane Sesquiterpenes from the Fungus Lentinus conatus BCC 8996. J Nat Prod 68:1674-1676.

Pittayakhajonwut P, Suvannakad R, Thienhirun S, Prabpai S, Kongsaeree P, Tanticharoen M (2005) An anti-herpes simplex virus-type 1 agent from Xylaria mellisii (BCC 1005). Tetrahed Lett 46(8):1341-1344.

Prajoubklang A, Sirithunyalug B, Charoenchai P, Suvannakad R, Sriubolmas N, Piyamongkol S, Kongsaeree P, Kittakoop P (2005) Bioactive deoxypreussomerins and dimeric naphthoquinones from Diospyros ehretioides fruits: Deoxypreussomerins may not be plant metabolites but may be from fungal epiphytes or endophytes. Chern Biodivers 2(10):1358-1367.

Isaka M, Palasarn S, Kocharin K, Saenboonrueng J (2005) A cytotoxic xanthone dimer from the entomopathogenic fungus Aschersonia sp. BCC 8401. J Nat Prod 68(6):945-6.