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(Update September 2010)

Assay	Primary screening (Bath/Sample)	IC₅₀ / MIC (Bath/Sample)
Cytotoxicity against cancerous cell lines KB (human, oral cavity, carcinoma) MCF-7 (human, breast, adenocarcinoma) NCI-H187 (human, small cell lung, carcinoma) HL-60 (human, leukemia) HepG2 (human, liver, hepatocarcinoma,) Caco-2 (human, colon, adenocarcinoma) B16-F10 (mouse, skin, melanoma)	200 200 200 350 - - -	600 600 600 1000 2500 2500 2500 **
Cytotoxicity against normal cell lines Vero (african green monkey, kidney, fibroblast) HEp-2 (human, larynx, epithelial) L929 (mouse, subcutaneous, connective tissue) 3T3 (mouse, embryonic, fibroblast) IEC6 (rat, small intestine, epithelial) BHK(21)C(13) (baby hamster, kidney, fibroblast) Human dermal skin fibroblast	300 - - - - - -	900 2500 2500 2500 2500 2500 2500
Cytotoxicity against insect cell lines Sf9 (Spodopthera frugiperda, pupal ovarian tissue) C6/36 (Aedes albopictus, mosquito larvae	- -	2500 2500
Anti-human infectious pathogens Anti-malaria (Plasmodium falciparum) Anti-TB (Mycobacterium tuberculosis) Anti-herpes simplex virus type 1 Anti-fungal (Candida albicans) Anti-bacteria (Bacillus cereus)	- 300 400 200 400	750 1000 1400 600 850
Anti-plant disease pathogens Anti- blast disease (Magnaportha grisea) Anti- dirty panicle disease (Curvularia lunata)	400 400	850 850
Neuraminidase inhibition assay (Avian influenza,H5N1)	450	700
Mycoplasma contamination test	1000	-

* IC₅₀ = Inhibitory concentration at 50 % inhibition, MIC =Minimum inhibitory concentration at 90% inhibition

** Report includes IC₅₀ + S.D. from three independent experiments. The assay is suitable for specific purposes such as pre-launched commercial and cosmetic products

Last Updated (Wednesday, 18 April 2012 08:56)

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