TRANSLATIONAL RESEARCH FACILITIES

A number of laboratories and facilities are established with special emphasis to promote translational research in collaboration with industry, as well as provide services to industry. These are:

Shrimp Genetic Improvement Center


This Center was established through collaboration between BIOTEC, Prince of Songkla University and Mahidol University. Located in Surat Thani Province, the Center serves as a production facility for the selective breeding of the black tiger shrimp Penaeus monodon. It has a large biosecurity area housing the hatchery, nursery and facilities to culture diatoms, artemia and polychaetes. The Center also has a wet lab for routine analyses and molecular biology work and a housing facility for conducting training. Through the network of various BIOTEC laboratories conducting shrimp research, this Center has access to technologies such as disease diagnosis, artificial insemination, genomic identification of shrimp families using microsatellite markers, EST, cryopreservation and traceability.


Nuclear Polyhedrosis Virus Pilot Plant for Insect Pest Control

npv3


This is a specially dedicated plant where the virus production is undertaken by natural mass rearing of worms infected by the virus. The facility consists of multiple clean rooms for mass rearing of worms, viral inoculation and harvesting. The facility is capable of producing three species of NPV namely; Spodoptera exigua NPV, Helicoverpa armigera NPV and Spodoptera litura NPV. Current commercial production is focused on Spodoptera exigua NPV and Spodoptera litura NPV. With access to expertise in entomology and virology, the Pilot Plant can develop the production of other viral biocontrol agents from different combinations of various viral strains and worm types. For more information, please contact:

Nuclear Polyhedrosis Virus Pilot Plant for Insect Pest Control
National Center for Genetic Engineering and Biotechnology
113 Thailand Science Park
Phaholyothin Road
Klong 1, Klong Luang
Pathumthani 12120, Thailand
Tel: +66 (0) 2564 6700 Ext. 3714
Fax: +66 (0) 2564 6528


Thailand Bioresource Research Center


Thailand Bioresource Research Center (TBRC)
serves as a store-front for vast arrays of biological material such as, microorganisms, cell lines, hybridoma cells, enzymes, etc. Through the linkage developed with the Thailand Network of Culture Collections and major culture collections in Asia, TBRC is able to provide comprehensive and diverse biological material to serve the needs of industrial clients. As the basic research on microorganisms is being carried out under one roof, bioinformation, such as gene sequences, enzyme screening results and a chemical compound database on each culture is also made available through sophisticated information systems software to facilitate the maximum utilization of microbial strains. To serve the country’s need for management of bioresources, TBRC also provides a management tool to support conservation and utilization of bioresources. 
Click here to view VDO presentation of Thailand Bioresource Research Center.


Food and Feed Innovation Center 


The Food and Feed Innovation Center is built upon the strength in starter culture technology, food chemistry and food safety available at the BIOTEC Food Biotechnology Research Unit, with state-of-the-art facilities for scale-up production. Access to rich bioresources at the Thailand Bioresource Research Center and core microbial technologies in enzyme discovery and heterologous expression systems offers a unique opportunity for the Center to incorporate the application of microbes in the development of niche products such as food ingredients (flavor enhancers, texturizers, etc.), probiotics, animal feed and feed supplements. Through the network of NSTDA research laboratories, expertise in nano-delivery at NANOTEC and polymer technology at MTEC can be tapped to extend the research and development to such topics as smart food packaging according to client interests.  The main facility of the Food and Feed Innovation Center consists of 300 L submerged fermentor and 500 kg solid state fermentor, with various downstream processes Click here to view VDO presentation of Food and Feed Innovation Center Center.


Integrative Biorefinery Laboratory


The Integrative Biorefinery Laboratory is established as a focal point for multi-disciplinary biorefinery research with the combined strength from BIOTEC and the Joint Graduate School of Energy and Environment (JGSEE), King Mongkut's University of Technology Thonburi, with alliance in NANOTEC and networks of leading local universities and international institutions. This strategic laboratory focuses on development of platform technology on conversion of the underutilized agricultural biomass and sugars to valorized fuels and chemicals by bio- and chemo-catalytic processes and on translation of technology to industrial application through contract and collaborative projects with industries. The facility is fully equipped with lab-scale high pressure thermal reactors and a catalytic reactor system for pretreatment, fractionation and conversion of biomass to fuels and chemicals. The laboratory is also equipped with bioreactors and standard bioprocess equipment. Process upscaling is studied in collaboration with units in BIOTEC and JGSEE. Click here to download a brochure.


Biopharmaceutical Facility


This GMP pilot plant facility is a result of collaboration between BIOTEC and King Mongkut's University of Technology Thonburi (KMUTT). Located at KMUTT Bangkhuntien Campus), this is Thailand's prime manufacturing facility of clinical grade biopharmaceuticals for first in-human studies, equipped with microbial and cell culture fermentation systems (both up to 500L) at Biosafety Level 2 (BSL2), supported by harvesting, purification, and aseptic fill and finish capabilities. The pilot plant has been designed to comply with international standards including US Food and Drug Administration (USFDA) and the Pharmaceutical Inspection Cooperation Scheme (PIC/S). The facility's research and development team provide expertise in process optimization, scale up, upstream process development, downstream process development and development of analytical methods in order to accelerate the delivery of laboratory results to the market.