Other centers under the NSTDA family include National Metal and Materials Technology Center (MTEC), National Electronics and Computer Technology Center (NECTEC), National Nanotechnology Center (NANOTEC) and Technology Management Center (TMC).

During 2007-2008, NSTDA and its centers underwent organization restructuring, with particular focus on research funding. From 1 October 2008, research funding activities and research program management are coordinated under the Cluster and Program Management Office under NSTDA, and BIOTEC now functions as a research institute, with a funding program specifically addressing platform technology development.

As a premier research institute in Thailand and Asia, BIOTEC operates research units located at Thailand Science Park and specialized laboratories hosted by various universities, employing 570 staff, of which 170 are PhD researchers and 200 research assistants and lab technicians (as of September 2013). BIOTEC research covers a wide spectrum from agricultural science to biomedical science and environmental science. Apart from research laboratories, BIOTEC activities also include policy research, an outreach program, training and international relations.

BIOTEC income is sourced from government funding and revenues from providing services/commercialization and non-government entities such as international funding agencies and private foundations.