Monoclonal Antibody Production and Application Research Team

BIOTEC

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Monoclonal Antibody Production
and Application Research Team

Monoclonal Antibody Production and Application Research Team (IMAT) has specialized in monoclonal antibody (MAb) production and immunodiagnostic assay development, mainly focusing on diagnosis for agricultural and food industry. Our goal is to provide diagnostic methods that are accurate,
inexpensive and deliverable to both private and public end users.

Mission

1) To develop antibodies and diagnostic methods for the agricultural and food industry, including the development of antibodies and diagnostic assays for the detection of plant pathogenic viruses and bacteria, food pathogenic bacteria and contaminants, animal pathogenic viruses and bacteria, and also the development of antibodies and diagnostic assays for the measurement of dairy cow hormone levels for efficient dairy farm management.

2) To develop biosensors for more efficient diagnostics, with the ability to test a large number of samples in a short period of time (high throughput) as well as the ability to test many types of targets simultaneously (multiplex detection).

3) To create the basic knowledge that helps support the development and extension of diagnostic technology, including the study on novel technology to increase the efficiency of antibody production, study on the distribution and diversity of plant pathogens, study on the relationships between plant pathogens / host plants / insect vectors, study on the development of efficient inoculation protocols for screening of virus- resistant plants, etc.

4) To establish the systematic hybridoma collection program with an effective database management system for deposition of valuable hybridoma clones developed by our laboratory and other institutes.

5) To provide services in scaling up and purification of monoclonal antibodies and commercialization of in-house antibodies and diagnostic test kits

6) For public interest, we have provided our in-house monoclonal antibodies to Thai researchers and students from various institutions for non-profit purposes to promote research and development in agriculture and diagnostics. Our team welcomes students and research interns from around the world. We offer them the opportunity to gain knowledge and experience in monoclonal antibody production and development of immunodiagnostic assays under the supervision of our experienced researchers. We also provide workshops and trainings on the production of monoclonal antibodies and the development of diagnostic tests using immunological techniques

Services provided

- Commercialization of in-house antibodies and diagnostic test kits
- Scaling up and purification of monoclonal antibody

- Antibodies for Detection of Plant Pathogens

- Immunochromatogrphic Strip Test for Detection of Bacterial Fruit Blotch Disease (Fruit Blotch Easy Kits)

- Immunochromatographic Strip Test for Multiplex Detection of Three Plant Pathogens in Cucurbits

- Enrichment-IMS-Plating Method for Detection of Live Acidovorax citrulli in Cucurbit Seeds

- Immunomagnetic Separation and Real Time PCR for Rapid Detection of Listeria monocytogenes in Food Samples

- Multiplex RT-PCR-ELISA System for Tospovirus Identification

- Monoclonal antibody and competitive ELISA for measurement of progesterone levels in serum and milk of dairy cattle